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中文名称：QDPR 抗原（重组蛋白）
英文名称： QDPR Antigen (Recombinant Protein)
别 名： quinoid dihydropteridine reductase; DHPR; PKU2; HDHPR; SDR33C1
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
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Fusion protein corresponding to a region derived from 2-244 amino acids of human QDPR |
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Full name: |
quinoid dihydropteridine reductase |
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Synonyms: |
DHPR; PKU2; HDHPR; SDR33C1 |
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Swissprot: |
P09417 |
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Gene Accession: |
BC000576 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase. |
