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中文名称： MCPH1 抗原（重组蛋白）
英文名称： MCPH1 Antigen (Recombinant Protein)
别 名： microcephalin 1; MCT; BRIT1
相关类别： 抗原
储 存： 冷冻（-20℃）
概 述
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Fusion protein corresponding to a region derived from 363-562 amino acids of human MCPH1 |
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Full name: |
microcephalin 1 |
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Synonyms: |
MCT; BRIT1 |
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Swissprot: |
Q8NEM0 |
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Gene Accession: |
BC030702 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described. |
