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中文名称： 兔抗MDM2多克隆抗体
英文名称： Anti-MDM2 rabbit polyclonal antibody
别 名： HDMX; hdm2; ACTFS
相关类别： 一抗
储 存： 冷冻（-20℃） 避光
宿 主： Rabbit
抗 原： MDM2
反应种属： Human
标 记 物： Unconjugate
克隆类型： rabbit polyclonal
技术规格
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Background: |
MDM2, a ubiquitin ligase for p53, plays a central role in regulation of the stability of p53 . Akt-mediated phosphorylation of MDM2 at Ser166 and Ser186 increases its interaction with p300, allowing MDM2-mediated ubiquitination and degradation of p53 . Phosphorylation of MDM2 also blocks its binding to p19ARF, increasing the degradation of p53 . |
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Applications: |
WB |
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Name of antibody: |
MDM2 |
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Immunogen: |
Synthetic peptide of human MDM2 |
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Full name: |
MDM2 oncogene, E3 ubiquitin protein ligase |
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Synonyms： |
HDMX; hdm2; ACTFS |
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SwissProt: |
Q00987 |
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WB Predicted band size: |
90 kDa |
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WB Positive control: |
293 and Hela cells |
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WB Recommended dilution: |
500-1000 |
