ÖÐÎÄÃû³Æ£º Íÿ¹MBP¶à¿Ë¡¿¹Ìå
Ó¢ÎÄÃû³Æ£º Anti-MBP rabbit polyclonal antibody
±ð Ãû£º MGC99675
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ËÞ Ö÷£º Rabbit
¿¹ Ô£º MBP
·´Ó¦ÖÖÊô£º Human, Mouse, Rat
±ê ¼Ç Î Unconjugate
¿Ë¡ÀàÐÍ£º rabbit polyclonal
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Background: |
The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation. |
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Applications: |
WB |
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Name of antibody: |
MBP |
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Immunogen: |
Synthetic peptide of human MBP |
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Full name: |
myelin basic protein |
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Synonyms£º |
MGC99675 |
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SwissProt: |
P02686 |
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WB Predicted band size: |
33 kDa |
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WB Positive control: |
Rat brain, Mouse brain and Rat hippocampus Tissue |
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WB Recommended dilution: |
500-1000 |

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