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中文名称： ITGB2 抗原（重组蛋白）
英文名称： ITGB2 Antigen (Recombinant Protein)
别 名： integrin, beta 2 (complement component 3 receptor 3
and 4 subunit); LAD; CD18; MF17; MFI7; LCAMB; LFA-1; MAC-1
储 存： 冷冻（-20℃）
相关类别： 抗原
概述
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Fusion protein corresponding to a region derived from 124-363 amino acids of human ITGB2 |
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Full name: |
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
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Synonyms: |
LAD; CD18; MF17; MFI7; LCAMB; LFA-1; MAC-1 |
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Swissprot: |
P05107 |
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Gene Accession: |
BC005861 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene. |
