ÖÐÎÄÃû³Æ£º Íÿ¹MATK¶à¿Ë¡¿¹Ìå
Ó¢ÎÄÃû³Æ£º Anti-MATK rabbit polyclonal antibody
±ð Ãû£º CHK; CTK; HYL; Lsk; HYLTK; HHYLTK
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ËÞ Ö÷£º Rabbit
¿¹ Ô£º MATK
·´Ó¦ÖÖÊô£º Human Mouse Rat
±ê ¼Ç Î Unconjugate
¿Ë¡ÀàÐÍ£º Unconjugate
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Background: |
The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene. |
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Applications: |
WB |
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Name of antibody: |
MATK |
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Immunogen: |
Synthesized peptide derived from Internal of human MATK. |
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Full name: |
megakaryocyte-associated tyrosine kinase |
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Synonyms£º |
CHK; CTK; HYL; Lsk; HYLTK; HHYLTK |
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SwissProt: |
P42679 |
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WB Predicted band size: |
56 kDa |
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WB Positive control: |
Jurkat cells lysate |
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WB Recommended dilution: |
500-3000 |

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