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021-54845833/15800441009
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Background: |
DEAD-box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure and ribosome/spliceosome assembly. Based on their distribution patterns, some members of this family may be involved in embryogenesis, spermatogenesis and cellular growth and division. DDX43 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 43), also known as CT13 or HAGE, is a 648 amino acid protein that contains one KH domain, one helicase C-terminal domain and one helicase ATP-binding domain and belongs to the DEAD-box family. Expressed in testis and present at abnormally high levels in a variety of tumors, DDX43 is thought to function as an ATP-dependent RNA helicase that may play a role tumor transformation and metastasis. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
DDX43 |
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Immunogen: |
Fusion protein of human DDX43 |
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Full name: |
DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 |
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Synonyms： |
CT13; HAGE |
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SwissProt: |
Q9NXZ2 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human thyroid cancer |
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IHC Recommend dilution: |
50-200 |
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WB Predicted band size: |
73 kDa |
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WB Positive control: |
HepG2 cells |
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WB Recommended dilution: |
200-1000 |
