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Ó¢ÎÄÃû³Æ£º OS9 Antigen (Recombinant Protein)

±ð      Ãû£º osteosarcoma amplified 9, endoplasmic reticulum lectin; OS-9; ERLEC2

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Fusion protein corresponding to a region derived from 108-350 amino acids of human OS9

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Full name:

osteosarcoma amplified 9, endoplasmic reticulum lectin

Synonyms:

OS-9; ERLEC2

Swissprot:

Q13438

Gene Accession:

BC007254

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

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