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021-54845833/15800441009
中文名称： IKBKE 抗原（重组蛋白）
英文名称： IKBKE Antigen (Recombinant Protein)
别 名： inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon; IKKE; IKKI; IKK-E; IKK-i
储 存： 冷冻（-20℃）
相关类别： 抗原
概述
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Fusion protein corresponding to C terminal 250 amino acids of human IKBKE |
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Full name: |
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon |
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Synonyms: |
IKKE; IKKI; IKK-E; IKK-i |
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Swissprot: |
Q14164 |
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Gene Accession: |
BC107812 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]). |
