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    SAA1 Antigen (Recombinant Protein)

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    serum amyloid A1; SAA; PIG4; SAA2; TP53I4

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    Fusion protein corresponding to a region derived from 19-122 amino acids of human SAA1

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    Full name:

    serum amyloid A1

    Synonyms:

    SAA; PIG4; SAA2; TP53I4

    Swissprot:

    P0DJI8

    Gene Accession:

    BC007022

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11.


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