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Ó¢ÎÄÃû³Æ£º GYPC Antigen (Recombinant Protein)

±ð      Ãû£º GE; GPC; GPD; GYPD; CD236; PAS-2; CD236R; PAS-2

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Fusion protein corresponding to N terminal 57 amino acids of human GYPC


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Full name:

glycophorin C

Synonyms:

GE; GPC; GPD; GYPD; CD236; PAS-2; CD236R; PAS-2

Swissprot:

P04921

Gene Accession:

BC104246

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants.


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