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    Ó¢ÎÄÃû³Æ£º FHL3 Antigen (Recombinant Protein)

    ±ð      Ãû£º SLIM2

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    Fusion protein corresponding to a region derived from 109-280 amino acids of human FHL3


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    Full name:

    four and a half LIM domains 3

    Synonyms:

    SLIM2

    Swissprot:

    Q13643

    Gene Accession:

    NP_004459

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    The protein encoded by this gene is a member of a family of proteins containing a four-and-a-half LIM domain, which is a highly conserved double zinc finger motif. The encoded protein has been shown to interact with the cancer developmental regulators SMAD2, SMAD3, and SMAD4, the skeletal muscle myogenesis protein MyoD, and the high-affinity IgE beta chain regulator MZF-1. This protein may be involved in tumor suppression, repression of MyoD expression, and repression of IgE receptor expression. Two transcript variants encoding different isoforms have been found for this gene.


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