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中文名称： ZGPAT 抗原（重组蛋白）
英文名称： ZGPAT Antigen (Recombinant Protein)
别 名： zinc finger CCCH-type and G-patch domain containing; ZIP; ZC3H9; GPATC6; GPATCH6; ZC3HDC9; KIAA1847
储 存： 冷冻（-20℃）
相关类别：抗原
概 述
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Full name: |
zinc finger CCCH-type and G-patch domain containing |
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Synonyms: |
ZIP; ZC3H9; GPATC6; GPATCH6; ZC3HDC9; KIAA1847 |
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Swissprot: |
Q8N5A5 |
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Gene Accession: |
BC019338 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis. |
