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    ÖÐÎÄÃû³Æ£º SLC12A4¿¹Ô­£¨ÖØ×éµ°°×£©

    Ó¢ÎÄÃû³Æ£º SLC12A4 Antigen (Recombinant Protein)

    ±ð       Ãû£º KCC1

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    Fusion protein corresponding to a region derived from 866-1085 amino acids of human SLC12A4

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    Full name:

    solute carrier family 12 (potassium/chloride transporters), member 4

    Synonyms:

    KCC1

    Swissprot:

    Q9UP95

    Gene Accession:

    BC021193

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    This gene encodes a member of the SLC12A transporter family. The encoded protein mediates the coupled movement of potassium and chloride ions across the plasma membrane. This gene is expressed ubiquitously. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May contribute to cell volume homeostasis in single cells. May be involved in the regulation of basolateral Cl- exit in NaCl absorbing epithelia.

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