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    ÖÐÎÄÃû³Æ£º  DCBLD2¿¹Ô­£¨ÖØ×éµ°°×£©

    Ó¢ÎÄÃû³Æ£º DCBLD2 Antigen (Recombinant Protein)

    ±ð      Ãû£º ESDN; CLCP1

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    Fusion protein corresponding to a region derived from 515-743 amino acids of human DCBLD2


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    Full name:

    discoidin, CUB and LCCL domain containing 2

    Synonyms:

    ESDN; CLCP1

    Swissprot:

    Q96PD2

    Gene Accession:

    BC029658

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    CLCP1 (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1), also known as DCBLD2 (discoidin, CUB and LCCL domain containing 2) or ESDN, is a 775 amino acid single-pass type I membrane protein that contains one CUB domain, one LCCL domain and one F5/8 type C domain. Expressed at high levels in heart, testis and skeletal muscle, CLCP1 is thought to regulate vascular smooth muscle cell (VSMC) proliferation and remodeling and may be involved in the transformation and metastasis of various cancers, such as metastatic lung cancer and gastric carcinoma.


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