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概述
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Full name: |
phosphatidylethanolamine binding protein 1 |
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Synonyms: |
PBP; HCNP; PEBP; RKIP; HCNPpp; PEBP-1 |
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Swissprot: |
P30086 |
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Gene Accession: |
BC031102 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Phosphatidylethanolamine-binding protein 1 is a protein that in humans is encoded by the PEBP1 gene. Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase By similarity. Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation. |
