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中文名称：ALDH4A1 抗原（重组蛋白）
英文名称： ALDH4A1 Antigen (Recombinant Protein)
别 名： aldehyde dehydrogenase 4 family, member A1; P5CD; ALDH4; P5C
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to C terminal 250 amino acids of human ALDH4A1 |
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Full name: |
aldehyde dehydrogenase 4 family, member A1 |
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Synonyms: |
P5CD; ALDH4; P5C |
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Swissprot: |
P30038 |
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Gene Accession: |
BC007581 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This protein belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. |
