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Background: |
Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits; this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency. |
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Applications: |
WB |
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Name of antibody: |
CPN1 |
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Immunogen: |
Synthesized peptide derived from C-terminal of human CPN1. |
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Full name: |
carboxypeptidase N, polypeptide 1 |
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Synonyms： |
CPN; SCPN |
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SwissProt: |
P15169 |
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WB Predicted band size: |
52 kDa |
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WB Positive control: |
RAW264.7 cells lysate |
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WB Recommended dilution: |
500-3000 |
