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Íÿ¹COL7A1¶à¿Ë¡¿¹Ìå


Ó¢ÎÄÃû³Æ£º Anti-COL7A1 rabbit polyclonal antibody

±ð      Ãû£º collagen type VII alpha 1 chain; EBD1; EBR1; EBDCT; NDNC8

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ËÞ      Ö÷£º Rabbit

¿¹      Ô­£º COL7A1

·´Ó¦ÖÖÊô£º Human

±ê ¼Ç Î Unconjugate

¿Ë¡ÀàÐÍ£º rabbit polyclonal

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Background:

This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen.

Applications:

ELISA, WB

Name of antibody:

COL7A1

Immunogen:

Synthetic peptide of human COL7A1

Full name:

collagen type VII alpha 1 chain

Synonyms:

EBD1; EBR1; EBDCT; NDNC8

SwissProt:

Q02388

ELISA Recommended dilution:

5000-10000

WB Predicted band size:

295 kDa

WB Positive control:

A172 cell lysate

WB Recommended dilution:

200-1000




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