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  • Íÿ¹CLK2¶à¿Ë¡¿¹Ìå

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Íÿ¹CLK2¶à¿Ë¡¿¹Ìå


Ó¢ÎÄÃû³Æ:Anti-CLK2 rabbit polyclonal antibody

´¢      ´æ:Àä¶³£¨-20¡æ£©

¿¹      Ô­:CLK2

ËÞ      Ö÷:Rabbit

·´Ó¦ÖÖÊô:Human, Mouse

Ïà¹ØÀà±ð:Ò»¿¹

±ê ¼Ç Îï:Unconjugate

¿Ë¡ÀàÐÍ:rabbit polyclonal

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Background:

This gene encodes a dual specificity protein kinase that phosphorylates serine/threonine and tyrosine-containing substrates. Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceosomal complex, thereby influencing alternative transcript splicing. Chromosomal translocations have been characterized between this locus and the PAFAH1B3 (platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)) gene on chromosome 19, resulting in the production of a fusion protein. Note that this gene is distinct from the TELO2 gene (GeneID:9894), which shares the CLK2 alias, but encodes a protein that is involved in telomere length regulation. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, IHC

Name of antibody:

CLK2

Immunogen:

Synthetic peptide of human CLK2

Full name:

CDC like kinase 2

SwissProt:

P49760

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer and human ovarian cancer

IHC Recommend dilution:

30-150






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