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Background: |
This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. |
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Applications: |
WB |
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Name of antibody: |
CHUK(Phospho-Ser176/177) |
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Immunogen: |
Peptide sequence around phosphorylation site of serine 176/177 (Q-G-S(p)-L-C) derived from Human IKK-alpha/beta. |
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Full name: |
conserved helix-loop-helix ubiquitous kinase |
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Synonyms： |
IKK1; IKKA; IKBKA; TCF16; NFKBIKA; IKK-alpha |
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SwissProt: |
O15111 |
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WB Predicted band size: |
85 kDa |
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WB Positive control: |
NIH/3T3 cells lysates treated with TNF |
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WB Recommended dilution: |
500-1000 |
