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        µ±Ç°Î»ÖÃ: Ê×Ò³ > ¿ÆÑвúÆ· > ¿ÆÑп¹Ìå > Ò»¿¹ > Íÿ¹GCSH¶à¿Ë¡¿¹Ìå

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        • Íÿ¹GCSH¶à¿Ë¡¿¹Ìå

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        ÖÐÎÄÃû³Æ£º Íÿ¹GCSH¶à¿Ë¡¿¹Ìå


        Ó¢ÎÄÃû³Æ£º Anti-GCSH rabbit polyclonal antibody


        ±ð       Ãû£º glycine cleavage system protein H; GCE; NKH


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        ´¢       ´æ£º Àä¶³£¨-20¡æ£©

        ËÞ       Ö÷£º Rabbit

        ¿¹       Ô­£º GCSH


        ·´Ó¦ÖÖÊô£º Human, Mouse, Rat


        ±ê  ¼Ç  Î Unconjugate


        ¿Ë¡ÀàÐÍ£º rabbit polyclonal


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        Background:

        Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). Two transcript variants, one protein-coding and the other probably not protein-coding,have been found for this gene. Also, several transcribed and non-transcribed pseudogenes of this gene exist throughout the genome.

        Applications:

        ELISA, IHC

        Name of antibody:

        GCSH

        Immunogen:

        Fusion protein of human GCSH

        Full name:

        glycine cleavage system protein H

        Synonyms:

        GCE; NKH

        SwissProt:

        P23434

        ELISA Recommended dilution:

        5000-10000

        IHC positive control:

        Human liver cancer and Human colorectal cancer

        IHC Recommend dilution:

        50-200





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