ÖÐÎÄÃû³Æ£ºÍÿ¹ABCD4¶à¿Ë¡¿¹Ìå
Ó¢ÎÄÃû³Æ£º Anti-ABCD4 rabbit polyclonal antibody
±ð Ãû£º P70R; P79R; ABC41; MAHCJ; PMP69; PXMP1L; EST352188
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ËÞ Ö÷£º Rabbit
¿¹ Ô£º ABCD4
·´Ó¦ÖÖÊô£º Human, Mouse
±ê ¼Ç Î Unconjugate
¿Ë¡ÀàÐÍ£º rabbit polyclonal
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Background: |
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in at least two different transcript variants, one which is protein-coding and one which is probably not protein-coding. |
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Applications: |
ELISA, WB |
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Name of antibody: |
ABCD4 |
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Immunogen: |
Synthetic peptide of human ABCD4 |
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Full name: |
ATP-binding cassette, sub-family D (ALD), member 4 |
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Synonyms£º |
P70R; P79R; ABC41; MAHCJ; PMP69; PXMP1L; EST352188 |
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SwissProt: |
O14678 |
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ELISA Recommended dilution: |
1000-2000 |
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WB Predicted band size: |
69 kDa |
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WB Positive control: |
Jurkat cells |
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WB Recommended dilution: |
200-1000 |
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021-54845833/15800441009
