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ÖÐÎÄÃû³Æ£º СÊó¿¹SHPKµ¥¿Ë¡¿¹Ìå

Ó¢ÎÄÃû³Æ£º Anti-SHPK mouse monoclonal antibody

±ð    Ãû£º CARKL; SHK

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ËÞ    Ö÷£º Mouse

¿¹    Ô­£º SHPK

·´Ó¦ÖÖÊô£º Human

±ê ¼Ç Î Unconjugate

¿Ë¡ÀàÐÍ£º mouse monoclonal

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Background:

The protein encoded by this gene has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases. The gene resides in a region commonly deleted in cystinosis patients, suggesting a role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, frequently involved in chromosomal rearrangements. [provided by RefSeq, Jul 2008].

Applications:

WB, IF

Name of antibody:

SHPK

Immunogen:

Fusion protein of human SHPK

Full name:

sedoheptulokinase (SHPK)

Synonyms:

CARKL; SHK

SwissProt:

Q9UHJ6

WB Predicted band size:

51 kDa

WB Positive control:

HepG2, SVT2 cell lysates

WB Recommended dilution:

200-1000



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