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Background: |
LTA4H (Leukotriene A4-hydrolase ) is a Zn2+-containing enzyme with both epoxide hydrolase and aminopeptidase activity. As an epoxide hydrolase, LTA4H catalyzes the hydration of LTA4 to leukotriene B4 (LTB4, 5S,12R-dihydroxy-6,14-cis-8,10-trans-eicosatetraenoic acid), a potent lipid chemoattractant that influences inflammation, immune responses, and host defense against infection. As an aminopeptidase, LTA4H catalyzes the cleavage of amides of para-nitroaniline. The human LTA4H gene encodes a 610 amino acid protein. |
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Applications: |
ELISA, WB |
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Name of antibody: |
LTA4H |
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Immunogen: |
Fusion protein of human LTA4H |
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Full name: |
leukotriene A4 hydrolase |
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SwissProt: |
P09960 |
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ELISA Recommended dilution: |
2000-5000 |
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WB Predicted band size: |
69 kDa |
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WB Positive control: |
TM4 cells |
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WB Recommended dilution: |
500-2000 |
