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Background: |
This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
LONP1 |
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Immunogen: |
Synthetic peptide of humanLONP1 |
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Full name: |
lon peptidase 1, mitochondrial |
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Synonyms： |
LON; LONP; PIM1; hLON; LonHS; PRSS15 |
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SwissProt: |
P36776 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human breast cancer and Human esophagus cancer |
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IHC Recommend dilution: |
25-100 |
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WB Predicted band size: |
106 kDa |
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WB Positive control: |
A431, NIH/3T3 and HepG2 cells, Mouse liver tissue and Hela cells |
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WB Recommended dilution: |
500-2000 |
