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Ó¢ÎÄÃû³Æ£ºFASTK Antigen (Recombinant Protein)

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Fusion protein corresponding to a region derived from C terminal 300 amino acids of humanFASTK


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Full name:

fas-activated serine/threonine kinase

Synonyms:

FAST

Swissprot:

Q14296

Gene Accession:

BC000377

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined.


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