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COL3A1 Antigen (Recombinant Protein)

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Fusion protein corresponding to a region derived from 154-345 amino acids of human COL3A1


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Full name:

collagen, type III, alpha 1

Synonyms:

EDS4A

Swissprot:

P02461

Gene Accession:

BC028178

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.



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