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    CEACAM3 Antigen (Recombinant Protein)

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    Fusion protein corresponding to a region derived from 45-155 amino acids of human CEACAM3


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    Full name:

    carcinoembryonic antigen-related cell adhesion molecule 3

    Synonyms:

    CEA; CGM1; W264; W282; CD66D

    Swissprot:

    P40198

    Gene Accession:

    BC106728

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described.


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