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ÖÐÎÄÃû³Æ£º Íÿ¹FZD1¶à¿Ë¡¿¹Ìå

Ó¢ÎÄÃû³Æ£º Anti-FZD1 rabbit polyclonal antibody


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ËÞ       Ö÷£º Rabbit


¿¹       Ô­£º FZD1


·´Ó¦ÖÖÊô£º Human


±ê ¼Ç  Î Unconjugate


¿Ë¡ÀàÐÍ£º rabbit polyclonal

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Background:

Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Activated by Wnt3A, Wnt3, Wnt1 and to a lesser extent Wnt2, but not by Wnt4, Wnt5A, Wnt5B, Wnt6, Wnt7A or Wnt7B.

Applications:

ELISA, WB

Name of antibody:

FZD1

Immunogen:

Synthetic peptide of human FZD1

Full name:

Frizzled family receptor 1

SwissProt:

Q9UP38

ELISA Recommended dilution:

1000-2000

WB Predicted band size:

71 kDa

WB Positive control:

293T cells

WB Recommended dilution:

200-1000





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