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相关类别： 一抗
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Background: |
The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
IL2RB |
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Immunogen: |
Fusion protein of human IL2RB |
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Full name: |
interleukin 2 receptor, beta |
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Synonyms： |
CD122; IL15RB; P70-75 |
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SwissProt: |
P14784 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human thyroid cancer and human cervical cancer |
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IHC Recommend dilution: |
25-100 |
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WB Predicted band size: |
61 kDa |
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WB Positive control: |
231, 293T, Raji and hela cells |
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WB Recommended dilution: |
500-2000 |
