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021-54845833/15800441009
克隆类型： rabbit polyclonal
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Background: |
Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
IFT57 |
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Immunogen: |
Fusion protein of human IFT57 |
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Full name: |
intraflagellar transport 57 |
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Synonyms: |
HIPPI; MHS4R2; ESRRBL1 |
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SwissProt: |
Q9NWB7 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human tonsil |
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IHC Recommend dilution: |
50-300 |
