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021-54845833/15800441009
储 存： 冷冻（-20℃）
技术规格
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Background: |
This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
ICAM1 |
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Immunogen: |
Synthetic peptide of human ICAM1 |
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Full name: |
intercellular adhesion molecule 1 |
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Synonyms： |
BB2; CD54; P3.58 |
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SwissProt: |
P05362 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human lung cancer and Human breast cancer |
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IHC Recommend dilution: |
50-200 |
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WB Predicted band size: |
58 kDa |
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WB Positive control: |
Huvec, hela and raji cells |
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WB Recommended dilution: |
500-2000 |
