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    ÖÐÎÄÃû³Æ£ºÐ¡Êó¿¹LOXµ¥¿Ë¡¿¹Ìå

    Ó¢ÎÄÃû³Æ£º Anti-LOX mouse monoclonal antibody

    ±ð       Ãû£º MGC105112

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    ´¢      ´æ£º Àä¶³£¨-20¡æ£© ±Ü¹â

    ËÞ       Ö÷£º Mouse

    ¿¹        Ô­£º LOX

    ·´Ó¦ÖÖÊô£º Human , Dog , Rat

    ±ê  ¼Ç  Î Unconjugate

    ¿Ë¡ÀàÐÍ£º mouse monoclonal


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    Background:

    The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

    Applications:

    WB, IHC, IF, FC

    Name of antibody:

    LOX

    Immunogen:

    Fusion protein of human LOX

    Full name:

    lysyl oxidase (LOX), transcript variant 1

    Synonyms:

    MGC105112

    SwissProt:

    P28300

    IHC positive control:

    human colon tissue

    IHC Recommend dilution:

    10-50

    WB Predicted band size:

    47 kDa

    WB Positive control:

    MDCK, PC12 cell lysates

    WB Recommended dilution:

    500-2000

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