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    ÖÐÎÄÃû³Æ£ºÐ¡Êó¿¹IL18BPµ¥¿Ë¡¿¹Ìå

    Ó¢ÎÄÃû³Æ£º Anti-IL18BP mouse monoclonal antibody

    ±ð       Ãû£º interleukin 18 binding protein; IL18BPa

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    ´¢      ´æ£º Àä¶³£¨-20¡æ£©

    ËÞ      Ö÷£º Mouse

    ¿¹      Ô­£º IL18BP

    ·´Ó¦ÖÖÊô£º Human

    ±ê ¼Ç Î Unconjugate

    ¿Ë¡ÀàÐÍ£º Mouse Monoclonal

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    Background:

    The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

    Applications:

    WB

    Name of antibody:

    IL18BP

    Immunogen:

    Fusion protein of human IL18BP

    Full name:

    interleukin 18 binding protein

    Synonyms:

    IL18BPa

    SwissProt:

    O95998

    WB Predicted band size:

    21 kDa

    WB Positive control:

    K562 cell, CHO-K1 cell, CHO-K1 cells transfected by IL18BP-PDGFR fusion protein cell lysates

    WB Recommended dilution:

    200-1000



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