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中文名称 : 小鼠抗CYB5R1单克隆抗体
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Background: |
NADH-cytochrome b5 reductases participate in a variety of physiological processes including biosynthesis of cholesterol, methemoglobin reduction of erythrocytes, elongation of fatty acids and metabolism of drugs. CYB5R1 (cytochrome b5 reductase 1), also known as NADH-cytochrome b5 reductase 1, B5R1, NQO3A2, humb5R2 or NAD(P)H:quinone oxidoreductase type 3 polypeptide A2, is a 305 amino acid single-pass membrane protein that contains one FAD-binding FR-type domain and belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. Widely expressed, CYB5R1 binds FAD as a cofactor and is encoded by a gene located on human chromosome 1. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes, comprises nearly 8% of the human genome and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. |
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Applications: |
WB, IHC, IF |
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Name of antibody: |
CYB5R1 |
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Immunogen: |
Fusion protein of human CYB5R1 |
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Full name: |
cytochrome b5 reductase 1 (CYB5R1) |
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Synonyms: |
B5R.1; B5R1; B5R2; humb5R2; NQO3A2 |
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SwissProt: |
Q9UHQ9 |
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IHC positive control: |
adenocarcinoma of human endometrium tissue and human kidney tissue |
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IHC Recommend dilution: |
30-150 |
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WB Predicted band size: |
34 kDa |
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WB Positive control: |
A549 cell lysate |
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WB Recommended dilution: |
500-2000 |
