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021-54845833/15800441009
中文名称：小鼠抗CSE1L单克隆抗体
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Background: |
Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. |
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Applications: |
WB, IHC |
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Name of antibody: |
CSE1L |
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Immunogen: |
Fusion protein of human CSE1L |
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Full name: |
chromosome segregation 1 like |
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Synonyms: |
CAS; CSE1; XPO2 |
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SwissProt: |
P55060 |
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IHC positive control: |
Human kidney cancer and Human gastric cancer |
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IHC Recommend dilution: |
500-2000 |
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WB Predicted band size: |
110 KD |
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WB Positive control: |
Hela, Ramos cell lysates |
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WB Recommended dilution: |
200-1000 |
