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021-54845833/15800441009
中文名称：小鼠抗CDC42单克隆抗体
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Background: |
The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. |
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Applications: |
ELISA, WB |
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Name of antibody: |
CDC42 |
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Immunogen: |
Fusion protein of human CDC42 |
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Full name: |
cell division cycle 42 |
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Synonyms: |
TKS; G25K; CDC42Hs |
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SwissProt: |
P60953 |
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WB Predicted band size: |
21 kDa |
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WB Positive control: |
SW480 whole cell lysate |
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WB Recommended dilution: |
1000-5000 |
