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中文名称：兔抗CGAS多克隆抗体
英文名称： Anti-CGAS rabbit polyclonal antibody
别 名： cyclic GMP-AMP synthase; MB21D1; h-cGAS; C6orf150
相关类别： 一抗
储 存： 冷冻（-20℃）
抗 原： CGAS
宿 主： Rabbit
反应种属： Human
标 记 物： Unconjugate
克隆类型： rabbit polyclonal
技术规格
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Background: |
cGAS (cyclic GMP-AMP synthase), also known as MB21D1 (Mab-21 domain containing 1), h-cGAS or C6orf150, is a 522 amino acid cytoplasmic nucleotidyltransferase that catalyzes the formation of cyclic GMP-AMP (cGAMP) from ATP and GTP. cGAS is suggested to have antiviral activity by acting as a key cytosolic DNA sensor. cGAS binds to cytosolic DNA, which leads to cGAMP synthesis and activation of TMEM173, thereby trigger type-I interferon production. Expressed in monocytic cell line THP1, cGAS exists as two alternatively spliced isoforms and is encoded by a gene located on human chromosome 6q13. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
CGAS |
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Immunogen: |
Synthetic peptide of human CGAS |
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Full name: |
cyclic GMP-AMP synthase |
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Synonyms: |
MB21D1; h-cGAS; C6orf150 |
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SwissProt: |
Q8N884 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human liver cancer |
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IHC Recommend dilution: |
20-100 |
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WB Predicted band size: |
59 kDa |
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WB Positive control: |
HT-29 and Lovo cell lysates |
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WB Recommended dilution: |
500-2000 |
