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Anti-CEP290 rabbit polyclonal antibody

±ð      Ãû£º centrosomal protein 290; CT87; MKS4; POC3; rd16; BBS14; JBTS5; LCA10; NPHP6; SLSN6; 3H11Ag

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Rabbit

¿¹      Ô­£º CEP290

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Human, Mouse

±ê ¼Ç Î Unconjugate

¿Ë¡ÀàÐÍ£º rabbit polyclonal

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Background:

This gene encodes a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer.

Applications:

ELISA, IHC

Name of antibody:

CEP290

Immunogen:

Fusion protein of human CEP290

Full name:

centrosomal protein 290

Synonyms:

CT87; MKS4; POC3; rd16; BBS14; JBTS5; LCA10; NPHP6; SLSN6; 3H11Ag

SwissProt:

O15078

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer and Human gastric cancer

IHC Recommend dilution:

25-100






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