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    • Íÿ¹CEP290¶à¿Ë¡¿¹Ìå

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    ÖÐÎÄÃû³Æ£ºÍÿ¹CEP290¶à¿Ë¡¿¹Ìå

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    Anti-CEP290 rabbit polyclonal antibody

    ±ð      Ãû£º centrosomal protein 290; CT87; MKS4; POC3; rd16; BBS14; JBTS5; LCA10; NPHP6; SLSN6; 3H11Ag

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    Rabbit

    ¿¹      Ô­£º CEP290

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    Human, Mouse

    ±ê ¼Ç Î Unconjugate

    ¿Ë¡ÀàÐÍ£º rabbit polyclonal

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    Background:

    This gene encodes a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer.

    Applications:

    ELISA, IHC

    Name of antibody:

    CEP290

    Immunogen:

    Fusion protein of human CEP290

    Full name:

    centrosomal protein 290

    Synonyms:

    CT87; MKS4; POC3; rd16; BBS14; JBTS5; LCA10; NPHP6; SLSN6; 3H11Ag

    SwissProt:

    O15078

    ELISA Recommended dilution:

    5000-10000

    IHC positive control:

    Human thyroid cancer and Human gastric cancer

    IHC Recommend dilution:

    25-100






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