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021-54845833/15800441009
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Background: |
Rex-1 (for reduced expression), also designated zinc finger protein 42 (ZFP42), is an acidic zinc finger protein. Rex-1 contains four repeats of the zinc finger nucleic acid-binding motif and a potential acidic activator domain, suggesting that it is a regulatory protein. Rex-1 localizes to the nucleus and is highly expressed in embryonic stem (ES) and undifferentiated murine F9 teratocarcinoma cells. At the transcriptional level, expression of Rex-1 is reduced when F9 cells are induced to differentiate by the addition of retinoic acid (RA), and Rex-1 repression is enhanced by E1A. The Oct-3/4 transcription factor can either activate or repress the Rex-1 promoter, depending on the cellular environment, while Oct-6 can lower the expression of Rex-1. |
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Applications: |
ELISA, WB |
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Name of antibody: |
ZFP42 |
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Immunogen: |
Synthetic peptide of human ZFP42 |
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Full name: |
ZFP42 zinc finger protein |
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Synonyms： |
REX1; ZNF754 |
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SwissProt: |
Q96MM3 |
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ELISA Recommended dilution: |
1000-2000 |
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WB Predicted band size: |
35 kDa |
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WB Positive control: |
A549, K562 and PC3 cells |
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WB Recommended dilution: |
200-1000 |
