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ÖÐÎÄÃû³Æ£ºÍÿ¹CDC42EP5¶à¿Ë¡¿¹Ìå

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Anti-CDC42EP5 rabbit polyclonal antibody

±ð      Ãû£º CEP5; Borg3

¿¹      Ô­£º CDC42EP5

´¢      ´æ£º Àä¶³£¨-20¡æ£© ±Ü¹â

ËÞ      Ö÷£º Rabbit

·´Ó¦ÖÖÊô£º Human Mouse

Ïà¹ØÀà±ð£º Ò»¿¹

±ê ¼Ç Î Unconjugate

¿Ë¡ÀàÐÍ£º Unconjugate

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Background:

Cell division control protein 42 (CDC42), a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg (binder of Rho GTPases) family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to CDC42 and regulate its function negatively. The encoded protein may inhibit c-Jun N-terminal kinase (JNK) independently of CDC42 binding. The protein may also play a role in septin organization and inducing pseudopodia formation in fibroblasts

Applications:

WB

Name of antibody:

CDC42EP5

Immunogen:

Synthesized peptide derived from N-terminal of human BORG3.

Full name:

CDC42 effector protein (Rho GTPase binding) 5

Synonyms£º

CEP5; Borg3

SwissProt:

Q6NZY7

WB Predicted band size:

15 kDa

WB Positive control:

Jurkat cells lysate

WB Recommended dilution:

500-3000




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