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中文名称： 兔抗ZFAND2A多克隆抗体
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Background: |
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZFAND2A (AN1-type zinc finger protein 2A) is a 171 amino acid protein containing two AN1-type zinc fingers. AN1-type zinc fingers contain six conserved cysteines, two histidines and have a dimetal (zinc)-bound alpha/beta fold. The gene encoding ZFAND2A maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
ZFAND2A |
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Immunogen: |
Synthetic peptide of human ZFAND2A |
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Full name: |
zinc finger AN1-type containing 2A |
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Synonyms: |
AIRAP |
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SwissProt: |
Q8N6M9 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human brain |
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IHC Recommend dilution: |
25-50 |
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WB Predicted band size: |
16 kDa |
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WB Positive control: |
293T cell lysate |
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WB Recommended dilution: |
500-2000 |
