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    ÖÐÎÄÃû³Æ£ºÍÿ¹CD59¶à¿Ë¡¿¹Ìå

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    Anti-CD59 rabbit polyclonal antibody

    ±ð      Ãû£º CD59 molecule (CD59 blood group); 1F5; EJ16; EJ30; EL32; G344; MIN1; MIN2; MIN3; MIRL; HRF20; MACIF; MEM43; MIC11; MSK21; 16.3A5; HR

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    ËÞ      Ö÷£º Rabbit

    ¿¹      Ô­£º CD59

    ·´Ó¦ÖÖÊô£º Human

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    Unconjugate

    ¿Ë¡ÀàÐÍ£º rabbit polyclonal

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    Background:

    This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.

    Applications:

    ELISA, IHC

    Name of antibody:

    CD59

    Immunogen:

    Fusion protein of human CD59

    Full name:

    CD59 molecule (CD59 blood group)

    Synonyms:

    1F5; EJ16; EJ30; EL32; G344; MIN1; MIN2; MIN3; MIRL; HRF20; MACIF; MEM43; MIC11; MSK21; 16.3A5; HRF-20; MAC-IP; p18-20

    SwissProt:

    P13987

    ELISA Recommended dilution:

    5000-10000

    IHC positive control:

    Human liver cancer

    IHC Recommend dilution:

    200-300




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