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    ÖÐÎÄÃû³Æ£ºÍÿ¹CD22¶à¿Ë¡¿¹Ìå

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    Anti-CD22 rabbit polyclonal antibody

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    SIGLEC2; SIGLEC-2

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    ¿¹      Ô­£º CD22

    ËÞ      Ö÷£º Rabbit

    ·´Ó¦ÖÖÊô£º Human

    ±ê ¼Ç Î Unconjugate

    ¿Ë¡ÀàÐÍ£º rabbit polyclonal

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    Background:

    The B lymphocyte specific CD22 antigen, also designated B-lymphocyte cell adhesion molecule (BLCAM), sialic acid-binding Ig-like lectin 2 (Siglec-2) and Leu-14, is a type I integral membrane glycoprotein, structurally similar to other cell adhesion molecules (CAMs), which acts as a regulator of B cell signaling. CD22 is expressed as both a cytoplasmic and membrane protein during discrete stages of B cell lymphocyte differentiation. The cytoplasmic form of CD22, expressed early in B cell development, is a useful marker for acute lymphocytic leukemia. The membrane form of CD22 is expressed in mature B cells prior to their differentiation into plasma cells.

    Applications:

    ELISA, IHC

    Name of antibody:

    CD22

    Immunogen:

    Fusion protein of human CD22

    Full name:

    CD22 molecule

    Synonyms:

    SIGLEC2; SIGLEC-2

    SwissProt:

    P20273

    IHC positive control:

    Human gastric cancer and human thyroid cancer

    IHC Recommend dilution:

    50-200




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