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Ó¢ÎÄÃû³Æ£º Anti-CCR5(Phospho-Ser349) rabbit polyclonal antibody
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ËÞ Ö÷£º Rabbit
¿¹ Ô£º CCR5(Phospho-Ser349)
·´Ó¦ÖÖÊô£º Human
±ê ¼Ç Î Unconjugate
¿Ë¡ÀàÐÍ£º Unconjugate
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Background: |
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). |
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Applications: |
WB |
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Name of antibody: |
CCR5(Phospho-Ser349) |
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Immunogen: |
Peptide sequence around phosphorylation site of Serine 349 (E-I-S(p)-V-G) derived from Human CCR5. |
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Full name: |
chemokine (C-C motif) receptor 5 (gene/pseudogene) |
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Synonyms£º |
CKR5; CCR-5; CD195; CKR-5; CCCKR5; CMKBR5; IDDM22; CC-CKR-5 |
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SwissProt: |
P51681 |
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WB Predicted band size: |
41 kDa |
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WB Positive control: |
A549 cells lysates |
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WB Recommended dilution: |
500-1000 |

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