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    ÖÐÎÄÃû³Æ£ºÍÿ¹CAV1¶à¿Ë¡¿¹Ìå

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    Anti-CAV1 rabbit polyclonal antibody

    ±ð       Ãû£º CGL3; PPH3; BSCL3; VIP21; MSTP085

    Ïà¹ØÀà±ð£º Ò»¿¹

    ´¢      ´æ£º Àä¶³£¨-20¡æ£©

    ËÞ      Ö÷£º Rabbit

    ¿¹      Ô­£º CAV1

    ·´Ó¦ÖÖÊô£º Human, Mouse, Rat

    ±ê ¼Ç Î Unconjugate

    ¿Ë¡ÀàÐÍ£º rabbit polyclonal

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    Background:

    The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.

    Applications:

    ELISA, WB

    Name of antibody:

    CAV1

    Immunogen:

    Synthetic peptide of human CAV1

    Full name:

    caveolin 1, caveolae protein, 22kDa

    Synonyms£º

    CGL3; PPH3; BSCL3; VIP21; MSTP085

    SwissProt:

    Q03135

    ELISA Recommended dilution:

    2000-5000

    WB Predicted band size:

    20 kDa

    WB Positive control:

    Human leiomyosarcoma tissue

    WB Recommended dilution:

    500-2000





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