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Ó¢ÎÄÃû³Æ£º CD247 Antigen (Recombinant Protein)

±ð    Ãû£º CD247 molecule; T3Z; CD3H; CD3Q; CD3Z; TCRZ; IMD25; CD3-ZETA

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Fusion protein corresponding to a region derived from 22-164 amino acids of human CD247

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Full name:

CD247 molecule

Synonyms:

T3Z; CD3H; CD3Q; CD3Z; TCRZ; IMD25; CD3-ZETA

Swissprot:

P20963

Gene Accession:

BC025703

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.


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