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    ÖÐÎÄÃû³Æ£ºÍÿ¹ATXN3¶à¿Ë¡¿¹Ìå

    Ó¢ÎÄÃû³Æ£º Anti-ATXN3 rabbit polyclonal antibody

    ±ð      Ãû£º ATXN3; AT3; ATX3; JOS; MJD; MJD1; SCA3

    Ïà¹ØÀà±ð£º Ò»¿¹

    ´¢      ´æ£º Àä¶³£¨-20¡æ£© ±Ü¹â

    ËÞ      Ö÷£º Rabbit

    ¿¹      Ô­£º ATXN3

    ·´Ó¦ÖÖÊô£º Human, Mouse, Rat

    ±ê ¼Ç Î Unconjugate

    ¿Ë¡ÀàÐÍ£º rabbit polyclonal

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    Background:

    Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

    Applications:

    WB

    Name of antibody:

    ATXN3

    Immunogen:

    Fusion protein of human ATXN3

    Full name:

    ataxin 3

    Synonyms£º

    ATXN3; AT3; ATX3; JOS; MJD; MJD1; SCA3

    SwissProt:

    P54252

    WB Predicted band size:

    43 kDa

    WB Positive control:

    MCF7 cells

    WB Recommended dilution:

    500-2000



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