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021-54845833/15800441009
中文名称：兔抗APOE多克隆抗体
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Background: |
Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants |
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Applications: |
WB |
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Name of antibody: |
APOE |
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Immunogen: |
Synthesized peptide derived from C-terminal of human APOE. |
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Full name: |
apolipoprotein E |
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Synonyms： |
AD2; LPG; LDLCQ5 |
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SwissProt: |
P02649 |
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WB Predicted band size: |
36 kDa |
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WB Positive control: |
K562 cells lysate |
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WB Recommended dilution: |
500-3000 |
